Proteasome-mediated Degradation of Rac1-GTP during Epithelial Cell Scattering
نویسندگان
چکیده
منابع مشابه
Proteasome-mediated degradation of Rac1-GTP during epithelial cell scattering.
Epithelial cells disassemble their adherens junctions and "scatter" during processes such as tumor cell invasion as well as some stages of embryonic development. Control of actin polymerization is a powerful mechanism for regulating the strength of cell-cell adhesion. In this regard, studies have shown that sustained activation of Rac1, a well-known regulator of actin dynamics, results in the a...
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ژورنال
عنوان ژورنال: Molecular Biology of the Cell
سال: 2006
ISSN: 1059-1524,1939-4586
DOI: 10.1091/mbc.e05-08-0779